Lec 5

• What is the abbreviation for the Kell Blood Group System?

  K
• What is the antibody class for the Kell Blood Group System?

  IgG
• At what optimal reaction temperature does the Kell Blood Group System react?

  37°C
• What is the reaction phase for the Kell Blood Group System?

  AHG
• What is the effect of enzyme treatment on the Kell Blood Group System?

  No effect
• What are the antigens in the Kell Blood Group System?

  • K (Kell)
  • k (Cellano)
  • Kp a
  • Kp b
  • Kp c
  • Js a
  • Js b
  • Ku
• What is the abbreviation for the Duffy Blood Group System?

  Fy
• What is the antibody class for the Duffy Blood Group System?

  IgG
• At what optimal reaction temperature does the Duffy Blood Group System react?

  37°C
• What is the reaction phase for the Duffy Blood Group System?

  AHG
• What is the effect of enzyme treatment on the Duffy Blood Group System?

  Destroys Fy a and Fy b
• What are the clinically significant aspects of the Duffy Blood Group System?

  • Anti-Fy a and anti-Fy b can cause HTR and HDN.
  • The Fy(a-b-) phenotype is more resistant to malarial infection by Plasmodium vivax.
• What are the antigens in the Duffy Blood Group System?


  • Fy a
  • Fy b
• What is the abbreviation for the Kidd Blood Group System?


  Jk
• What is the antibody class for the Kidd Blood Group System?

  IgG
• At what optimal reaction temperature does the Kidd Blood Group System react?

  37°C
• What is the reaction phase for the Kidd Blood Group System?

  AHG
• What is the effect of enzyme treatment on the Kidd Blood Group System?

  Enhances agglutination
• What are the clinically significant aspects of the Kidd Blood Group System?

  • Associated with HTR and mild HDN.
• What are the antigens in the Kidd Blood Group System?


  • Jk a
  • Jk b
  • Jk3
• What is the abbreviation for the Lutheran Blood Group System?

  Lu
• What are the antibody classes for the Lutheran Blood Group System?


  Lu a IgM; Lu b IgG
• What are the optimal reaction temperatures for the Lutheran Blood Group System?

  Lu a 4°C; Lu b 37°C
• What are the reaction phases for the Lutheran Blood Group System?

  Lu a room temperature; Lu b AHG
• What is the effect of enzyme treatment on the Lutheran Blood Group System?

  Variable effect
• What are the clinically significant aspects of the Lutheran Blood Group System?

  • No clinical significance for Anti-Lu a.
  • Anti-Lu b is rare and associated with HTR and HDN.
• What are the antigens in the Lutheran Blood Group System?

  • Lu a
  • Lu b
• What is the abbreviation for the Lewis Blood Group System?


  Le
• What is the antibody class for the Lewis Blood Group System?

  IgM
• At what optimal reaction temperature does the Lewis Blood Group System react?

  Most often 4°C, sometimes 37°C
• What are the reaction phases for the Lewis Blood Group System?

  Room temperature, 37°C, and AHG
• What is the effect of enzyme treatment on the Lewis Blood Group System?

  Enhanced agglutination
• What are the clinically significant aspects of the Lewis Blood Group System?

  • No clinical significance.
• What is the abbreviation for the I Blood Group System?

  I
• What is the antibody class for the I Blood Group System?

  IgM
• At what optimal reaction temperature does the I Blood Group System react?

  4°C
• What are the reaction phases for the I Blood Group System?

  Immediate spin (IS) and occasionally 37°C
• What is the effect of enzyme treatment on the I Blood Group System?

  Enhanced agglutination
• What are the clinically significant aspects of the I Blood Group System?

  • No clinical significance.
• What is the abbreviation for the P Blood Group System?

  P