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Biochemistry//
Metabolism of amino acids
1 proteins
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Proteins
Macromolecular nitrogen-containing
compounds
composed
of many
amino
acids
linked by
peptide
bonds
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Proteins are the most abundant organic compounds and constitute a major part of the body
dry weight
(
10-12
kg in adults)
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Functions of proteins
Static
(structural)
Dynamic
(enzymes,
hormones
, clotting factors,
receptors
)
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Biological importance of proteins
Important
components
of organisms
Important
biological
function
Can be
oxidized
to produce
energy
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Proteins are important components of
organisms
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Proteins have important
biological
functions
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Proteins can be
oxidized
to produce
energy
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Distribution of proteins
All
organs
Tissues
Each
cell
Each part of the
cell
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Proteins account for
45
% of the dry weight of the human body (even
80%
in
organs
and
tissues
such as
spleen
,
lung
, and
striated muscle
)
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Biological functions of proteins
Biological
catalyst
(enzyme)
Regulation
on metabolism
Immunological
protection
Transportation
and
storage
of
substances
Taking
part in signal
transduction
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A bout half of the body protein (predominantly
collagen
) is
present
in the
supportive
tissue
(
skeleton
and
connective
) while the other half is
intracellular
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Protein
turnover
Protein
turnover
is the
balance
between
protein synthesis
and
protein degradation