equine herpes virus EHV1,4 are the strains we are trying to vaccinate against in the UK. Respiratory disease is the most common type of herpes virus, this is endemic (affects almost horses under the age of 2) but is usually mild and the horse is only off colour (pyretic with nasal discharge) for two days. However, there can also be some more serious conditions as pregnant mares that are affected. When the respiratory disease is spread to the mare it can lead to abortion, stillbirth, and neonatal death.