The Krebs Cycle

• Acetate is removed from Coenzyme A and combines with a 4C oxaloacetate to form 6C sugar, citrate, Coenzyme A goes back to link reaction; citrate is decarboxylated and dehydrogenated, and 2 H+ ions are used to reduce NAD
• 5C molecule generates ATP (substrate-level phosphorylation); it’s decarboxylated and dehydrogenated, producing a 4C molecule, another CO_2 and reduced NAD, 4C is dehydrogenated, producing 2 H+ ions and reduced FAD
• For each molecule of glucose, Krebs cycle turns twice, producing: 4 carbon dioxides (waste product), 6x reduced NAD (to the ETC), 2x reduced FAD (to the ETC) and 2x ATP
• Krebs Cycle happens in matrix of mitochondria

  A) 2

  B) acetyl CoA

  C) CoA

  D) 4

  E) oxaloacetic acid

  F) 6

  G) citric acid

  H) CO_2

  I) NAD

  J) NADH + H^+

  K) 1 ATP

  L) CO_2

  M) 2NAD

  N) 2NADH

  O) FAD

  P) FADH_2