proteins mock

    Cards (36)

    • what are proteins made of and how many different ones are there
      20 different amino acids
    • what elements do proteins contain
      carbon, hydrogen, oxygen, nitrogen and some contain sulfur
    • draw and label an amino acid
    • What are the bonds between amino acids called?
      peptide bonds
    • how are the bonds between amino acids made
      condensation reaction - the water molecule is fromed by combining an OH from the carboxyl group from one amino acid and a H from the amino group of another amino acid
    • Which parts of amino acids are involved in a peptide bond?
      the C of the carboxyl group and the N of the amino group of the other amino acid
    • what affects the shape of a polypeptide
      the types of bonding between the amino acids in the chain
    • what shape do polypeptides have and why
      a precise 3D shape which is vital for the function e.g. enzymes
    • what are the 4 types of bonds that affect the shape of a polypeptide
      - hydrogen (weakest)
      - ionic
      - hydrophobic/hydrophilic interactions
      - disulfide
    • how do ionic bonds form
      between positively and negatively charged R groups
    • how do hydrophobic/hydrophillic interactions form in proteins
      interactions between hydrophobic non-polar R groups and a hydrophilic polar R group. the polar group folds out to face polar water. the non-polar will fold in to avoid polar water --> helps protein to fold
    • How do disulfide bonds form?
      between the sulfur-containing groups of two cysteine (an amino acid) molecules. they could be in the same chain (intrachain) or between different chains (interchain). this is a strong covalent bond
    • What is the primary structure of a protein?
      sequence of amino acids in a polypeptide chain --> different sequences = different proteins
    • What is the secondary structure of a protein?
      the start of protein folding, they form alpha helix (within the chain) or beta pleated sheets (between parallel chains), both are held by hydrogen bonds
    • What is the tertiary structure of a protein?
      the way in which a protein coils to form a precise 3D shape - made up of one amino acid chain - disulfide, hydrophobic/phillic, ionic and hydrogen bonding help to maintain the shape (intra-disulfide)
    • What is the quaternary structure of a protein?
      two or more polypeptide chains (subunits) joined together held together by the 4 types of bonds
    • what are the 3 types of quaternary structure proteins
      globular, fibrous, conjugated
    • what are globular proteins
      spherical, water soluble proteins
    • How do globular proteins form?
      the hydrophobic R groups fold away from the water and on the inside of the protein and the hydrophilic R groups fold outwards to face the water
    • Why are globular proteins soluble and why do they need to be
      the hydrophilic R groups are on the outside of the protein so they can travel in the blood
    • what are some types of globular proteins and an example
      enzymes e.g. amylase and hormones e.g. insulin which regulates blood glucose concentration
    • what are conjugated proteins
      Globular proteins that contain a non-protein component called a prosthetic group that is attached by either hydrogen, covalent or ionic bonds
    • give an example of a conjugated proteins
      haemoglobin
    • what is haemoglobin
      the red, oxygen-carrying pigment found in red blood cells
    • what is the structure of the protein part of haemoglobin
      globular: 4 polypeptides: two alpha and two beta subunits
    • How does haemoglobin carry oxygen?
      each polypeptide chain has a prosthetic group called a haem group. each haem group has an iron ion Fe2+, which can join with an oxygen molecule so it can carry 4 oxygens at one time
    • What are fibrous proteins?
      proteins formed from long, insoluble molecules
    • what is the structure of fibrous
      they are made up of small number of repeating amino acids and a high proportion of cysteine molecules to form disulfide bridges or bonds
    • properties of fibrous proteins
      insoluble and strong but have important structural roles
    • examples of fibrous proteins
      keratin, elastin and collagen
    • Where is keratin found?
      external structures like skin, hair, nails --> can be flexible e.g. in skin or hard and tough e.g. in nails
    • where is elastin found
      in elastic connective tissue such as skin, larger blood vessels and in alveoli in lungs so they can stretch and recoil
    • where is collagen found
      connective tissues that need mechanical strength e.g. bone, skin and muscle
    • what is a dipeptide?
      two amino acids joined together
    • why do some proteins not have a quaternary structure?
      they only contain one polypeptide chain
    • what are the types of bonds in each of the levels of protein structure?
      primary: peptide bonds
      secondary: hydrogen bonds and peptide bonds
      tertiary: ionic, disulfide, hydrogen and hydrophobic and hydrophilic interactions
      quaternary: same as tertiary