genes involved

• COMT gene

  involved in regulating dopamine levels, if this gene is deleted high levels of dopamine can cause symptoms of schiz
• DISC1 gene

  codes for creation of GABA, neurotransmitter that regulates other neurotransmitters like glutamate and dopamine.

  • Kim 2012, people with abnormality in this gene are 1.4 times more likely to develop schiz than those without the abnormality.