CBH 22 Cartilage

• Types of cartilage

  Hyaline elastic fibrocartilage
• Why cartilage is a specialized CT

  1. It is a tough, durable form of supporting connective tissue characterized by an extracellular matrix (ECM) with high concentrations of GAGs and proteoglycans2. Ideal for mechanical and protective roles3. It is an avascular tissue and also lacks nerves
• cells


  Chondrocytes embedded in the ECM they synthesize all the ECM components and are located in cavities called lacunae
• Extracellular matrix

  Type ii collagen(provides resistance)proteoglycans: hyalurananaggrecan with GAGs (chondroitin sulfate and keratin sulfate)Glycoproteins(chondronectin)
• Hyaline Cartilage location

  Located in: upper respiratory tract, articular ends, epiphyseal plates of long bones and constitutes fetal skeleton

  
• Hyaline cartilage


  Serves as a precursor for the embryonic development and subsequent growth of many long bones chondrocytes in insigenous groups presence of perichondrium prolonged repair due to a lack of blood vessels and nerves
• Elastic cartilage


  Type ii collagen, aggrecan and abundant elastic fibres presence of perichondrium provides flexibility of soft tissues

  
• Location of elastic cartilage

  The external ear, auditory tube, epiglottis, and other laryngeal cartilages
• Fibrocartilage


  Type ii collagen and large areas of dense connective tissue with type i collagen , NO perichondrium provides cushioning and resistance

  
• Location of fibrocartilage


  Present in intervertebral discs other jointsinsertions of tendons