can be broadly divided into two categories: ✓ Ex vivo gene therapy ✓ In vivo gene therapy
GermlineGeneTherapy
Cells are modified by the introduction of functional genes into their genomes, This effect will be passed on to the patient’s children & subsequent generations because gene transfer can occur in all cells of the developing embryo
Germline Gene Therapy
there is a possibility of permanently removing an inherited disorder from a family line. However, it is not done on humans because of ethical issue and fear of altering the human genes.