Biological evolution is the change in the properties of organisms over the course of generations, passed via genetic material into the next generation.
Ontogeny, or development/growth, of organisms is not evolution.
Plato believed that variation is an accidental imperfection.
Humans are genetically more diverse within populations than between populations.
Humans are less genetically differentiated than other mammals.
Humans have more genetic variation within a population than chimpanzees do between subspecies.
Genetic diversity in humans follows a gradient, indicating that there is not a "fixed" classification possible.
Aristotle believed that species have fixed properties, such as humans being able to talk and walk on two feet.
Christians believe that God's creation, the "great chain of being", must be permanent and unchanging as change implies imperfection.
Carolus Linnaeus proposed a catalogue plan of creation, known as systema naturae, for the classification of animals and plants.
Lamarck proposed that species originated spontaneously, that evolution aims to get more complex, and that there are no common ancestors between species.
Darwin proposed that all species have descended from one “original” forms of life, that there are five theories of natural selection, and that characteristics of lineages change over time.
Different species arose from one single common ancestor, according to Darwin.
Costly punishment: punishment and threat are strategies to enforce cooperation.
Indirect reciprocity: observer recognizes what others are doing and pick who cooperates.
Elastic population: extrapolative offspring by cooperation.
Global competition: cooperation will lead to higher success probability.
Iteration: learning and reciprocal interaction.
Tit-for-tat: players react to opponents last move (cooperate first and then copy other).
Inelastic population: individuals can't grow by helping, as it indirectly harms others.
Prisoner’s dilemma: Snowdrift game is better if you defect in both scenarios.
Win-stay-lose-shift: players react to the opponents and their own last move (if you win you repeat, if you lose you change strategy).
Conditional cooperation: individuals can decide whether to cooperate or not.
Selection mainly acts on the individual as the carrier of genes and not on a whole group.
Generalized reciprocity: own decisions are based on previous positive interaction.
Natural selection is the process where only those individuals who are adapted best will survive and get into the next generation, also known as survival of the fittest.
Variational evolution implies that individuals in an evolving population vary from one to another, and that these variations may accumulate during evolution due to a sorting process by which some variants become either more or less common.
A phylogeny, or evolutionary tree, represents the evolutionary relationships among a set of organisms, called taxa, with the tips of the tree representing groups of descendent taxa and the nodes on the tree representing the common ancestors of those descendants.
Bacteria often interact through the secretion of small molecules, with competition involving the release of toxins to fight each other, and cooperation involving the sharing of resources through enzymes.
Tumors consist of multiple cell lineages, making them unique and hard to treat, and interaction between tumor lineages can be either negative or positive.
Peto’s paradox states that there is no correlation between cancer incidences and body mass longevity.
Life history trade-offs involve dark skin, having fewer babies, growing up in a clean environment, and evolutionary mismatch.
Elephants have 20 tumor suppressor genes and a better DNA repair mechanism than mice, leading to fewer mutations.
A bottom-up approach to microbiome assembly involves ecological dynamics, evolutionary dynamics, and identifying forces that lead to healthy microbiomes.
Cancer evolution involves a multistep mutational process, is associated with chromosomal instability, and tumor mutations need to be on both copies to be harmful.
Cancer therapy involves targeting selfish or neutral cells and cooperational cell lines, which provide services to others.
Coalescence analysis allows tracking back to the most recent common ancestor.
Microbial interaction involves the assembly of microbiomes through a top-down approach, starting with complex samples, sequencing, descriptive analyses, and correlation with disease.
The cancer lottery involves lifestyle factors such as diet and smoking, genetic disposition, exposure to mutagenic agents, and evolutionary trade-offs.
Evolutionary trade-offs involve DNA double strand breaks, tissue regeneration, and inflammation.