Alveolar epithelium and capillary endothelium are very thin (1 cell thick)
Shortens diffusion distance of gases from alveoli to blood - only has to diffuse through two cells
Large number of alveoli
Increases surface area for gas exchange
Capillaries that surround the alveoli are very narrow
Red blood cells are slowed down to squeeze through one at a time increasing the time for diffusion
Large number of capillaries around alveoli
Circulation constantly removes oxygenated blood to maintain steep concentration gradient
Constant ventilation of air in and out of lungs
Ensures concentration of oxygen in alveoli is higher and concentration of carbon dioxide is lower than blood and therefore maintains steep concentration gradient