W3: Second Messenger Signalling

Subdecks (2)

Cards (20)

  • biofilms are bacteria living in a community of self produced extracellular polymeric substances (EPS) by attaching to a living/nonliving surface
  • free bacteria (planktonic) use flagella to move while bacteria in biofilm use pili to adhere/attach to its surface
  • biofilms have many functions, EPS acts as scaffold which contains openings and channels that allow for the flow of nutrients and waste and fulfills many beneficial roles for bacteria within it
    • localized gradients
    • sorption -> resource capture
    • enzyme retention -> external digestion system
    • cooperation -> metabolic cross feeding
    • competition -> continuous regeneration
    • tolerance/resistance
  • bacteria in aqueous environments have short lived interactions while biofilms facilitate prolonged bacterial interactions (good and bad) like communication (quorum), cooperation, and competition, this helps increase survivability in hostile environments
  • stages of biofilm life cycle
    1. initial adhesion -> planktonic bacteria use pili to attach to solid surfaces
    2. early development -> buildup of biofilm matrix through synthesis of exopolysaccharides/EPS
    3. mature biofilm -> cells adopt dormant state which makes it harder to kill
    4. biofilm dispersal -> released biofilm fragments diffuse to new locations and cycle restarts