when two amino acids are joined together, they are no longer complete, called an amino acid residue
moiety - protein or nonprotein part
catabolism of proteins
most catabolism of proteins occurs in digestive tract
proteins broken into amino acids
catabolism of proteins
catabolism also occurs in the kidneyandliver
amino acids are deaminated
albumin
Adult levels are 3.5 - 5.5 g/dL
Levels slightly lower during first year of life
albumin
Found decreased in inadequate amino acid supplies
Malnutrition - not getting enough protein in diet, so decreases
Muscle wasting diseases
a-1 globulins increases in inflammatory reactions, pregnancy, contraceptive use
biggest danger of trypsin: catabolize structural proteins via hydrolysis
a-1 fetoproteins
Levels of AFP rise by 13 weeks gestation and then fall dramatically just before the 34th week of gestation
Complex of haptoglobin and hemoglobin is removed by mononuclear phagocytic system (previously known as reticuloendothelial system) within minutes of formation
a-2 microglobulin controls site and/or extent of inflammation
b2-microglobulin is usually filtered out by glomerulus but reabsorbed in proximal tubule
biuret method
Reagent contains antioxidant and a chemical to prevent copper precipitation in alkaline solutions
