Most clinically important member of this group
Can cause rheumatic fever, acute glomerulonephritis, cellulitis, tonsillopharyngitis, impetigo, erysipelas, puerperal sepsis, toxic shock syndrome
Post-streptococcal sequelae include acute rheumatic fever and acute glomerulonephritis
Identified through rapid latex antigen kits
Treatment includes penicillin, clarithromycin or azithromycin, and clindamycin