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PBSCI EE
Pbsci Prelim
Tissue
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Four major types
Epithelial
2.
Connective
(many components)
3.
Muscle
4.
Nervous
EPITHELIAL TISSUES
CHARACTERISTICS
Cells are closely
packed without any
intercellular spaces
Lie on basement
membrane
Simple cubodial
–
o single layer of cube-shaped cells
o line kidney tubules
o cover ovaries
o line ducts of some glands
Simple columnar
–
o single layer of elongated cells
o nuclei usually near the basement
o membrane at same level
o sometimes possess cilia
o sometimes possess microvilli
o often have goblet cells
o line uterus, stomach, intestines
Pseudostratified columnar
–
o single layer of elongated cells
o nuclei at two or more levels
o appear striated
o often have cilia
o often have goblet cells
o line respiratory passageways
Simple squamous
–
o single layer of flat cells
o substances pass easily through
o line air sacs
o line blood vessels
o line lymphatic vessels
Keratinised Squamous Epithelium
(skin)
Found on dry
surfaces subjected
to wear and tear.
Consists of dead
epithelial cells that
have lost their
nuclei and contain
the protein keratin.
Sites
Skin, hairs and nails
Non-Keratinised Epithelium
Protects
moist
surfaces subjected
to wear and tear
and prevents them
from
drying
out.
Sites
Conjunctiva
of the
eyes, the lining of
the mouth, the
vagina.
Stratified squamous
–
many cell layers
top cells are flat
can accumulate keratin
outer layer of skin
line oral cavity, vagina, and anal canal
Stratified cuboidal
–
2-3 layers
cube-shaped cells
line ducts of mammary glands, sweat
glands, salivary glands, and the
pancreas
Stratified columnar
–
top layer of elongated cells
cube-shaped cells in deeper layers
line part of male urethra and part of
pharynx
Transitional
–
many cell layers
cube-shaped and elongated cells
line urinary bladder, ureters, and part of
urethra
TRANSITIONAL EPITHELIUM
Composed
of several
layers of
pear
shaped cells
which are
very elastic
and have
the capacity
of dividing
themselves.
Sites
Lines several parts of the urinary tract
including the bladder.
TYPES OF EPITHELIAL MEMBRANES
Serous
Mucous
Cutaneous
Synovial
Serous
(GI tract?)
line body cavities that
do not open to the
outside
reduce friction
inner lining of thorax
and abdomen
cover organs of thorax
and abdomen
secrete serous fluid
Mucous
line tubes and organs
that open to outside world
lining of mouth, nose, throat,
etc.
secrete mucus
Cutaneous
covers body
skin
Synovial
composed entirely of connective tissue
lines joints
GLANDULAR EPITHELIUM
Composed of cells that are specialized to produce and secrete substances
o Endocrine glands are ductless
o Exocrine glands have ducts
o Unicellular exocrine gland
composed of one cell
goblet cell
o Multicellular exocrine gland
composed of many cells
sweat glands, salivary glands, etc.
simple and compound
TYPES OF GLANDULAR SECRETIONS
Merocrine
glands
fluid product
salivary glands
pancreas
sweat glands
Apocrine
glands
cellular product
portions of cells
mammary glands
ceruminous glands
Holocrine
glands
secretory products
whole cells
sebaceous gland
FUNCTIONS OF EPITHELIAL TISSUES
Role of defense and protect the body organs
Secrete gastric juice in stomach
Absorb digested food in intestine
Removes waste
as
sweat
in
skin
CONNECTIVE TISSUES
(CT)
are a group of tissues which connects or
binds other tissues in the body.
GENERAL CHARACTERISTICS
-
most abundant tissue type
many functions
bind structures
provide support and protection
serve as frameworks
fill spaces
store fat
produce blood cells
protect against infections
help repair tissue damage
have a matrix
have varying degrees of vascularity
have cells that usually divide
CONNECTIVE TISSUE MAJOR CELL TYPES
Fibroblasts
fixed cell
most common cell
large, star-shaped
produce fibers
Mast cells
fixed cell
release heparin
release histamine
Macrophages
wandering cell
phagocytic
important in injury
or infection
CONNECTIVE TISSUE MAJOR CELL TYPES
Fibroblasts
They are large cells with irregular processes
Manufacture collagen and elastic fibres and a
matrix of extracellular material.
Functions:
Active in tissue repair
Fat cells
Also known as adipocytes
These cells occur singly or in groups in many
types of connective tissues and are especially
abundant in adipose tissue.
CONNECTIVE TISSUE MAJOR CELL TYPES
Macrophages
These are large irregular shaped cells
with granules in the cytoplasm
Important part of the body defence
mechanism because they are actively
phagocytic, engulfing and digesting cell
debris, bacteria and other foreign
bodies.
Leucocytes
White blood cells are normally found
in small numbers in healthy connective
tissues.
Synthesis and secret specific defensive
antibodies into the blood and tissue
Mast cells
Similar to basophilic
CONNECTIVE TISSUE MAJOR CELL TYPES
leukocytes
Found in loose connective tissues,
under the fibrous capsules of some
organs. eg.liver and spleen.
CONNECTIVE TISSUE FIBERS
Collagenous
fibers (strength/dense)
thick
composed of collagen
great tensile strength
abundant in dense CT
hold structures together
tendons, ligaments
Reticular
fibers (supportive)
very thin collagenous fibers
highly branched
form supportive networks
BUENO, M.
Elastic
fibers (stretch)
bundles of microfibrils embedded in
elastin
fibers branch
elastic
vocal cords, air passages
CONNECTIVE TISSUE FIBERS
Connective tissue proper
loose connective tissue
adipose tissue
reticular
connective tissue
dense connective tissue
elastic connective tissue
Specialized connective tissue
cartilage
bone
blood
Loose connective tissue
mainly fibroblasts
fluid to gel-like matrix
collagenous fibers
elastic fibers
bind skin to structures
beneath most epithelia
blood vessels nourish
nearby epithelial cells
between muscles
Adipose tissue
adipocytes
cushions
insulates
store
fats
beneath
skin
behind
eyeballs
around
kidneys
and
heart
WHITE ADIPOSE TISSUES
More present in obesity and in less in those
who are underweight
Found in between muscle fibres and under the
skin, where it acts as a thermal insulator and
energy store.
Sites
Deeper layer of skin, buttocks, breast and
around kidneys
BROWN ADIPOSE TISSUE (newborns)
Present in the newborn
Has a more extensive capillary network than
white adipose tissue.
Produces less energy and more heat than other
fat contributing to the maintenance of body
temperature.
Reticular connective tissue
composed of reticular fibers
supports internal organ walls
walls of liver, spleen, lymphatic organs
Dense connective tissue
packed collagenous fibers
elastic fibers
few fibroblasts
bind body parts together
tendons, ligaments, dermis
poor blood supply
Dense connective tissue
Elastic
connective tissue
Fibrous
tissue
Elastic connective tissue
abundant in elastic fibers
some collagenous fibers
fibroblasts
attachments between bones
walls of large arteries, airways, heart
Bone
(
Osseous Tissue
)
calcium lvl
solid matrix
supports
protects
forms blood cells
attachment for muscles
skeleton
osteocytes in lacunae
Cartilage
rigid matrix
chondrocytes in lacunae
poor blood supply
three types
hyaline
elastic
fibrocartilage
Hyaline cartilage
most abundant
ends of bones
nose, respiratory passages
embryonic skeleton
Elastic cartilage
flexible
external ear, larynx
Fibrocartilage
very tough
shock absorber
intervertebral discs
pads of knee and pelvic girdle
CARTILAGE
cells are sparse and lei embedded in matrix
reinforced by collagen and elastic fibres.
HYALINE CARTILAGE
It is a smooth
bluish white
tissues. The
chondrocytes
are arranged in
small groups
within cell
nests and
matrix is solid and smooth.
Function:
Provides flexibility, support and smooth
surfaces for movements at joints.
Sites:
Ends of long bones
Forming the parts of larynx, trachea and
bronchi
FIBROCARTLIAGE
Consists of dense
masses of white
collagen fibres in
a matrix similar
to that of hyaline
cartilage with the
cells widely
dispersed.
It is a tough, slightly flexible, supporting
tissue.
Sites
Pads between intervertebral disc
Between pubic bones(symphysis pubis)
ELASTIC FIBROCARTILAGE
Contains large amount
of elastin fibres in the
chondrin .
It's highly flexible
Sites
The pinna or lobe of ear, epiglottis
See all 45 cards
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