Stuff I need to know

• Liver Enzyme Inducers?

  St John's Wart

  Carbamazepine

  Phenytoin

  Topiramate

  Rifampicin

  Ritonavir
• Increased APPT = Haemophilia
• DIC:

  Prolonged APTT and PT

  Decreased fibrinogen and platelets
• Haemophilia A = Low factor 8
• Haemophilia B = Low factor 9
• Von Willebrand = decreased factor 8, normal PT, prolonged APTT
• Young woman = MS
• Central scotoma = optic neuritis visual defect (MS)
• Aeur Rods = AML
• Reed- Sternberg Cells = Hodgkin Lymphoma
• Thyroglossal cyst = moves on tongue pertrusion
• NHL= atypical lymphoid cells, irregular nucleus and high mitotic rate
• Myelofibrosis = tear drop poikilocytes
• Sickle cell = Autosomal recessive
• Factor 8 deficiency = prolonged PT
• Amyloidosis = Congo Red
• target cells = thalassemia
• Neuroleptic Malignant Syndrome = Rigid, delirium and infection

  High CK on bloods
• Seretonin Syndrome = mental state changes, autonomic hyperactivity, neuromuscular abnormalities
• Lithium Toxicity = Tremor, CNS dysfunction, arrhythmia, visual disturbances
• TACO = High BP

  TRALI = Low BP
• New onset psychosis, Schizophrenia or Mania without agitation = Risperidone etc
• Mania with agitation = Benzo
• Bipolar maintenance = Lithium
• Antipsychotic = Dopamine antagonist
• Aripiprazole = Lower prolactin
• Frontal = Broca's area = speech production
• Temporal = Wernicke's area = processing auditory stimuli
• SLE = warm auto-immune haemolytic anaemia
• IgG = most common paraprotein in myeloma
• Smudge cells = CLL
• Burkitt Lymphoma = EBV
• Epidural Haemorrhage = Lemon
• Subdural Haemorrhage = Cresent
• CN Nuclei

  A) Olfactory

  B) Optic

  C) Oculomotor

  D) Trochlear

  E) Trigeminal

  F) Abducens

  G) Vestibulocochlear

  H) Hypoglossal

  I) Accessory

  J) Vagus

  K) Glossopharyngeal

  L) Facial

  
• lateral geniculate body = vision
• medial geniculate body = auditory
• Sensory spinal pathways = ascending

  Motor spinal pathways = descending ]
• Dorsal column medial lemniscus:

  Sensory pathway

  Split into fasiculus cutaneous and fasiculus gracilis

  For fine touch, vibration and proprioception of ipsilateral side

  Dessucates in medulla
• Anterolateral spinothalamic pathway:

  Sensory pathway

  Lateral = pain and temp

  Anterior = crude touch and pressure

  Of contralateral side

  Dessucates in spinal cord