Blood vessels

Cards (14)

  • Systemic system
    • high pressure from the left ventricle to the capillary bed due to contraction
    • Pressure drop at capillary bed
    • low pressure from the capillary bed to right atrium
    • high pressure = High velocity of flow
    • Low pressure = low velocity of flow
    • From the ventricle to the capillary bed the total cross sectional area is increasing
    • Low pressure at the capillary bed due to a huge total cross sectional area
    • From the capillary bed to the right atrium there is a decrease in total cross sectional area
  • Capillaries
    • Exchange surface between blood and body cells
    1. Large surface area - lots of them, large total cross sectional are
    2. Thin for short diffusion pathway - endothelial cells = 1 cell thick
    3. Moist - capillaries are surrounded by tissue fluid and can exchange materials with it
    4. Permeable - the walls have gaps/fenestrations which allows exchange of fluid
    5. Maintain a concentration gradient - good blood supply
  • Oxygen, glucose and amino acids diffuse into tissue fluid then into the body cell down a diffusion/concentration gradient.
    Maintaining a concentration gradient - oxygen and glucose are used in aerobic respiration - amino acids are used in protein synthesis
    Heat may leave body fluid
  • Reducing velocity of flow
    = more time for the exchange of molecules
    • red blood cells have a larger diameter than the lumen of the capillary = increased friction = increased resistance to blood flow
    • decreased pressure due to increased total cross sectional area
  • Blood
    Plasma:
    • water
    • oxygen
    • glucose
    • amino acids
    • hormones
    • mineral salts (ions)
    • heat
    • carbon dioxide
    • urea
    • large plasma protein
    Cells:
    • Erythrocytes - red blood cells
    • White blood cells
    • Platlets
  • Large plasma proteins are too large to leave fit out of fenestrations in the capillary wall - they are retained in the capillary - and maintain the low water potential of the blood
  • At the arteriole end of the capillaries the hydrostatic pressure is high.
    At the venule end of the capillaries the hydrostatic pressure is low
  • Fluid exits the capillaries due to the high hydrostatic pressure.
    Fluid goes in due to low hydrostatic pressure and higher osmotic pressure
  • pressure is maintained in the aorta by elastic recoil of the elastic fibres
  • Artery structure:
    Out to in
    A) Tunica externa (collagen fibres)
    B) Tunica Media (smooth muscle and elastic fibres)
    C) Tunica Interna (smooth endothelium)
    D) basement membrane
  • Artery structure and function:
    • Thick wall to resist and sustain high pressure
    • Smooth endothelium - one cell thick - smooth lining to reduce friction and minimise resistance to flow
    • Thick layer of elastic fibres and smooth muscle to accommodate changes in blood flow and pressure as the blood is pumped out of the heart - stretch and recoil
    • Outer layer of connective tissue (collagen fibres) resist over-stretching
    • Narrow lumen to maintain high pressure
    • Arterioles use smooth muscle to adjust diameter - vasoconstriction/vasodilation
    • contains high pressure blood flowing away from the heart
  • Capillary structure and function:
    • Connects small arteries with small veins and allows exchange of materials with tissues across the capillary wall which is:
    • thin for a short diffusion pathway - 1 cell thick
    • narrow diameter = slow moving blood which allows time for exchange
    • pores/fenestrations leak to allow exchange pf materials e.g. small solute materials and ions through the endothelial cells
  • Vein structure and function:
    • thinner wall (especially muscle layer) as the pressure in the blood is now reduced
    • smooth endothelium - 1 cell thick - smooth lining to reduce friction and minimise resistance to flow
    • Outer layer of collagen to resist stretching
    • Has a wider lumen than arteries
    • Valves along their length to ensure flow of blood in one direction under low pressure - called pocket valves
    • Low pressure blood flowing towards the heart
  • Vein structure:
    out to in
    A) Tunica externa (collagen fibres)
    B) Tunica Media (smooth muscle and elastic fibres)
    C) Tunica Interna (smooth endothelium)
    D) basement membrane