MTAP - CC2

• Liver Function Tests:

  • Liver receives 15 mL of blood per minute
  • Synthetic function includes proteins, CHO, lipids, LPP, clotting factors, ketone bodies, enzymes
  • Albumin: 12g/day
  • Conjugation function involves bilirubin metabolism with Bilirubin at 200mg/day
  • Detoxification and Drug metabolism process ammonia to urea for excretion
  • Excretory and Secretory functions include bile acids (cholic acid and chenodeoxycholic acid) and bile salts (bile acids + amino acids - glycine and taurine)
  • Storage function for vitamins and glycogen
  • Test measuring the Hepatic Synthetic Ability: Total Protein Determination using various methods like Kjeldahl, Biuret, Folin-Ciocalteu, UV absorption, Electrophoresis, Refractometry, Turbidimetric and Nephelometric methods, Salt fractionation
• Prothrombin Time is a test measuring the Vitamin K Response, while the Bilirubin Assay tests the Conjugation/Excretion Function using methods like Evelyn and Malloy, Jendrassik and Grof, and the Bromsulfonphthalein (BSP) Dye Excretion test