Long Term Depression

• LTD - Long-lasting and experience-dependent weakening of synaptic connections between neurons that are not regularly coactivated
• Infrequent or insufficient release of neurotransmitters into the synaptic gap weakens the neural synapse
• LTD results in a decrease of receptor sites on postsynaptic dendrites as well as the dendrites themselves, and the synaptic connections between neurons
• A structural change of LTD would be less neurons and increases the inhibitory affects