•The sympathetic nervous system is primarily involved in responses that help us to deal with emergencies.•It responds to a perceived threat.•Neurons from the SNS travel to virtually every organ and gland within the body to produce physiological changes that prepare the body for fight or flight.•E.g. pupils dilate, causes the body to release stored energy, heart rate and breathing increase, non-vital functions are inhibited e.g. digestion and urination.