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Histology LEC
The Cell
The Cell Part 3
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Vesicles
: spherical-shaped membrane-bound sacs that contain various types of materials to be transported through the cell.
What do you call the transport cellular material?
Vesicle
Lysosome
: Spherical- shaped membrane-bound organelles formed from the GOLGI APPARATUS
What type of enzyme does LYSOSOME has?
Digestive
enzyme
What organelle digests MICROBES or Materials?
Lysosome
Lysosomes can be visualized by what type of microscope and by using what stain?
Light
microscope with
TOLUIDINE BLUE
Peroxisomes
: Smaller, spherical-shaped membrane-bound organelles formed from the ER or through FISSION
What type of enzyme does PEROXISOMES has?
Oxidative
enzymes
What organelle detoxifies specific harmful substances either produced by the cell or taken Into the cell?
Peroxisome
Peroxisomes engage in what?
Beta oxidation
of
fatty acids
to
acetyl CoA
Mitochondria
: Double membrane-bound organelles containing a circular strand of DNA
Mitochondria synthesize most
ATP
during
AEROBIC
cellular respiration by digestion of fuel molecules (e.g.
GLUCOSE
) in the presence of
OXYGEN.
Where does glycolysis takes place?
Cytoplasm
Where does the KREBS CYCLE takes place?
Mitochondrial matrirx
Ribosomes composed of both what?
Proteins
and
ribosomal RNA
Ribosomes engage in what synthesis?
Protein
synthesis
Which type of ribosomes produce PROTEINS that are secreted and incorporated into plasma membrane and within RIBOSOMES?
Bound ribosomes
Which type of ribosome produce proteins within the cell?
Free ribosomes
Cytoskeleton
: Organized network of protein filaments and hollow tubules, Including microfilaments, microtubules, and intermediate filaments
What organelle maintains intracellular structural support and organization of cells; participates in cell division: facilitates movement?
Cytoskeleton
Microtubules
: Heterodimers of aB-tubulin
Intermediate filaments
: Antiparallel tetramers of 2 rod-like dimers
Microfilaments
: 2 intertwined filaments of F-actin
Microtubules
: Hollow tube with a wall of 13 parallel protofilaments
Intermediate filaments
: ARRAYED throughout cytoplasm: at DESMOSOMES; inside nuclear envelop
Microtubules
: MAINTAIN cell's shape and
POLARITY
; provides tracks for organelle and chromosome movements as well as move
CILIA
and FLAGELLA
Microfilaments
: G-actin monomers
Intermediate filaments
: Cable of 4 intertwined PROTOFIBRILS, each consisting of bundled TETRAMERS associated end to end
Microtubules
: RADIATING through cytoplasm from concentration at CENTROSOMES; AXONEMES
Microfilaments
: Concentrated BENEATH cell membrane and in cell extensions like
MICROVILLI
Microfilaments
: CONTRACT and MOVE CELLS; CHANGE cell shape; cytokinesis, cytoplasmic transport and streaming
Intermediate filaments
: strengthen cell and
tissue
structure maintain
cell
shape and maintain NUCLEAR shape (
lamins
)
Centrosome
:
AMORPHOUS
region ADJACENT to nucleus
Centrosome
contains what?
a pair of
centrioles
Centrosome organizes what?
Microtubule
Centrosome
: participates in
MITOTIC SPINDLE
formation during cell division
Proteasomes
: Large, barrel-shaped protein complexes located in both the cytosol and nucleus
Proteasomes degrade and digest what?
damaged
and
unneeded
proteins
Proteasomes
: ensure quality of exported proteins
Inclusions
: Aggregates of specific types of molecules (eg, melanin protein, glycogen, or lipid)
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