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Patho exam practice
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Kim Zayas
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Cards (7)
Ankylosing Spondylitis
Chronic
lower back pain
and
stiffness,
worse in morning or
after
inactivity
Pain
and
stiffness
in
hips
,
shoulders,
and other
joints
, especially in advanced stages
Reduced
flexibility
and range of motion in
spine
and affected
joints
Fatigue
and
general discomfort
, especially during flare-ups
Fusion of the
spine
(
ankylosis
) leading to stooped posture and limited mobility in severe cases
View source
Fibromyalgia
Widespread musculoskeletal pain
and
tenderness
, often described as aching, burning, or throbbing
Fatigue
,
sleep disturbances
(such as
insomnia
or non-restorative sleep), and cognitive difficulties (fibro fog) affecting
memory
and concentration
Hypersensitivity
to touch, pressure,
temperature changes
, and
noise
Stiffness,
especially in the morning or after prolonged periods of rest
Headaches,
irritable bowel symptoms
, and
mood disturbances
(anxiety, depression)
View source
Gout
Sudden and
intense joint pain
, typically affecting the big toe (
podagra
), but can also occur in the ankles, knees, wrists, and fingers
Swelling
,
redness
, warmth, and tenderness in the affected joint
Limited range of motion due to
pain
and
inflammation
Recurrent episodes of
acute gouty arthritis
, often triggered by factors like diet (high purine foods),
alcohol
consumption, and certain medications
Chronic gout can lead to
joint
damage and
deformities
over time
View source
Muscular Dystrophy
(MD)
Progressive
muscle
weakness
and wasting, usually beginning in childhood or adolescence
Difficulty
with
motor
skills,
such as walking, running, climbing stairs, and lifting objects
Muscle
cramps,
stiffness
, and
contractures
(tightening of muscles and tendons) leading to joint stiffness and limited mobility
Respiratory
muscle
weakness
in some types of MD, causing breathing difficulties and
respiratory
infections
Delayed
motor milestones
in infants and children with MD
View source
Osteoarthritis
(
OA
)
Joint pain
, particularly after activity or at the end of the day, and worsens with
use
Stiffness
in the affected
joint
, especially in the morning or after periods of rest
Swelling, tenderness, and
warmth
around the
joint
Decreased
range of motion and
joint flexibility
Formation of
bone spurs
(
osteophytes
) and joint deformities over time
View source
During
interphase
the cell prepares by duplicating the
organelles
and the size of the cell grows in preparation for division.
View source
Progressive steps of cell malignancy
1.
initiation
2.
promotion
3.
progression
4.
angiogenesis
5.
evasion
6.
metastasis
View source
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