Excretion is the removal of waste substances, toxic materials and substances in excess
Waste products have toxic effects if allowed to reach high concentrations. For example, CO2dissolves in water easily to form an acidic solution, this lowers pH of cells and therefore reduces activity of enzymes.
Bodily fluids become more concentrated because of high amounts of waste products. Concentrated body fluids cause water to move out of cells by osmosis.Changes water potential and therefore preventing them from carrying out essential reactions