PCBI101 LEC: INTEGUMENTARY SYSTEM

Cards (156)

  • comprises the skin and its accessory organs like hair, nail and glands.
    The integumentary system
  • its capability to renew itself every 28 days.
    Skin
  • Five Layers of Epidermis:
    Come Lets Get Sun Burnt
    1. Stratum Corneum
    2. Stratum Lucidum
    3. Stratum Granulosum
    4. Stratum Spinosum
    5. Stratum Basale or Germinativum
  • The first layer of skin. It is made of a thin layer of squamous cells. This layer includes two distinct types: thick skin and thin skin. It consists of five layers.
    epidermis.
  • The first stage of wound healing is characterized by the formation of blood clots which aim to prevent too much blood loss.
    Hemostasis (Stoppage of bleeding)
  • The second layer of skin. It is made of dense, irregular connective tissue that houses blood vessels, hair follicles, sweat glands, and other
    structures. It consists of two layers.
    "Dermis""
  • also known as ""Corium."""
    Dermis
  • 2 layers of Dermis
    1. Papillary
    2. Reticular
  • The cascade of healing is divided into four overlapping phases:
    = Hemostasis
    = Inflammatory
    = Proliferative
    = Maturation
  • When the skin is injured, our body sets into motion an automatic series of events, often referred to as the
    CASCADE OF HEALING
  • Characterized by scabbing and clotting.

    Blood vessels around the wound narrow. This helps to stop the bleeding. Blood platelets, which are the clotting cells in the blood, clump together to make a “plug” in the wound. Clotting or coagulation includes a protein called "fibrin"". It’s “blood glue” that makes a net to hold the platelet plug in place which is the presence of a scab over the wound. Then, inflammation, which involves cleaning and healing."
    Inflammatory phase
  • Clotting or coagulation includes a protein called ____________. It’s “blood glue” that makes a net to hold the platelet plug in place which is the presence of a scab over the wound. Then, inflammation, which involves cleaning and healing.
    fibrin
  • Once the wound is clean and stable, the body can begin rebuilding the site of injury.

    Oxygen-rich red blood cells come to the site to create new tissue. Chemical signals in the body tell cells around the wound to make elastic tissues called collagen. This helps to repair the skin and tissues in the wound. Collagen is like a scaffold that other cells can be built on. At this stage in healing, a fresh, raised, red scar is visible. The scar will slowly fade in color and look flatter.
    Proliferative phase (Rebuilding & growth)
  • Chemical signals in the body tell cells around the wound to make elastic tissues called __________. This helps to repair the skin and tissues in the wound. ____________ is like a scaffold that other cells can be built on. At this stage in healing, a fresh, raised, red scar is visible. The scar will slowly fade in color and look flatter.
    Collagen
  • Even after your wound looks closed and repaired, it’s still healing.

    It has a pinkish color and a stretched skin
    appearance. Itching or tightness over the area can also be felt while the body continues to repair and strengthen the injured area
    Maturation phase (strengthening)
  • Is an organ system consist of skin and its accessory parts namely hair, nails, and exocrine glands.
    The Integumentary System
  • FUNCTIONS OF INTEGUMENTARY SYSTEM
    ï‚· Sensation
    ï‚· Heat regulation
    ï‚· Absorption
    ï‚· Protection
    ï‚· Excretion
    ï‚· Storage of fats
  • The skin is consists of three layers:
    = Epidermis
    = Dermis
    = Hypodermis
  • the outermost layer of skin, provides a waterproof barrier and creates our skin tone.
    Epidermis
  • beneath the epidermis, contains tough connective tissue, hair follicles, and sweat glands.
    Dermis
  • The deeper subcutaneous tissue is made of
    fat and connective tissue. It is well vascularized, with loose-areolar connective tissue and adipose tissue, for fat storage and provides insulation and acts as cushioning for the integument.
    Hypodermis
  • Also known as stratum germinativum; it is the deepest layer of epidermis.
    Stratum basale
  • The spiny layer of the epidermis.
    Stratum spinosum
  • It is composed of layers of "flattened keratinocytes" undergoing "apoptosis." Likewise, it has lamellar "granules" that release lip-rich secretion for water-repellent sealant to the skin.
    Stratum granulosum
  • This is the thickened skin of the palms and soles, composed of 4-6 layers of flat dead cells.
    Stratum lucidum
  • This is the outermost layer of the epidermis, which is formed by the accumulations of dead cells (keratinocytes) in the outermost epidermis, that are eventually shed. The rate of cell division increases where the skin is rubbed or where pressure is applied to the skin regularly, causing the growth of thickened areas called calluses on the palms and soles, and keratinized conical masses on the toes called corns
    Stratum corneum
  • also known as corium. It is consist of two layers: the papilary ad reticular
    The dermis
  • This layer is made of [ loose, areolar connective tissue. ] , Its superficial layer projects into the stratum basale of the epidermis to form [ finger-like dermal papillae. ]
    Papilary layer
  • This is the much thicker layer of the dermis
    consists of dense, [ irregular connective tissue.] This layer is well vascularized and has a rich sensory and sympathetic nerve supply. The reticular layer appears reticulated (net-like) due to a tight meshwork of fibers.
    Reticular layer
  • It refers to a [ bluish cast ] to the skin
    and mucous membranes.

    Peripheral ___________ is when there is a bluish discoloration to your hands or feet. It's usually caused by low oxygen levels in the red blood cells or problems getting oxygenated blood to your body
    Cyanosis
  • In __________, the skin and whites of
    the eyes look [ yellow. ] __________occurs when there is too much bilirubin (a yellow pigment) in the blood—a condition called hyperbilirubinemia.
    Jaundice
  • when there is too much bilirubin (a yellow pigment) in the blood—a condition called

    hyperbilirubinemia
  • It came from the Greek [ erythros ], meaning [red]. It is redness of the skin or mucous membranes, caused by hyperemia (increased blood flow) in superficial capillaries. It occurs with any skin injury, infection, or inflammation.
    Erythema
  • ï‚· A burn is a damage to body's tissues caused by heat, chemicals, electricity, sunlight, or radiation.
    BURN
  • LEVELS OF BURN
    = First-degree burns:
    = Second-degree burns:
    = Third-degree burns:
  • also known as “superficial burn” characterized by redness, minor swelling, pain and non-blistered skin.
    First-degree burns
  • more serious because the damage extends beyond the top layer of skin. with blisters and some thickening of the skin.
    Second-degree burns
  • widespread thickness with a white, leathery appearance.
    Third-degree burns
  • It is a genetic disorder that affects (completely or partially) the color of skin, hair, and eyes due to the inability of melanocytes to produce melanin.
    Albinism
  • A skin condition in which melanocytes in certain areas lose the ability to produce melanin, possibly due to an autoimmune reaction that leads to loss of color in patches.
    Vitiligo