Accessory organs of digestion are organs that secrete substances needed for the chemical digestion of food but through which food does not actually pass as it is digested. Besides the liver, the major accessory organs of digestion are the gallbladder and pancreas. These organs secrete or store substances that are needed for digestion in the first part of the small intestine, the duodenum, where most chemical digestion takes place. This organ includes the salivary glands, the liver, pancreas, and gallbladder.