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biosci lec 1
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Blood
Carries
oxygen
and nutrients to living cells and takes away waste products
Delivers immune cells to fight infections and it contains
platelets
60
% plasma
Plasma has
water
, proteins,
glucose
,
albumin
, clotting
factors
,
immunoglobulins
,
enzymes
,
antibodies
, and
sugar
and
fat
particles
Composed of white blood cells (
WBC
),
platelets
and red blood cells (
RBC
)
Red Blood Cell (Erythrocyte)
Biconcave
Carries oxygen
Contains
hemoglobin
Hemoglobin formation
1.
Heme
2.
Hemoglobin
3.
Erythrocytes
Hemoglobin contains
heme
, the heme contains
oxygen
, and the oxygen binds with
iron
Blood Circulation
1. Oxygenated blood goes into the lungs
2. Oxygen and CO2 exchange in the alveoli
3. Oxygenated blood returns to the heart and is pumped out to the whole body
Platelets
Originates from stem cells in the bone marrow
Forms clots
Irregularly shaped
Platelet-related diseases
Thrombocytopenia
Thrombocythemia
Von Willebrand Factor
One of the components of the platelets that makes them stick with each other
Platelets are activated in the presence of an injury and have an average life span of
9
days
before being excreted through the spleen
Low platelet count
Blood does not clot properly and flows outside the body
High platelet count
Causes blood clots without injury, leading to blockages in blood vessels and lack of blood flow to organs
Lack of blood flow to the heart muscle can lead to
heart attack
Neutrophils
Polymorphonuclear
Granulocytes
Function
is to
fight
off
pathogens
inside the body
Can permeate throughout the body
Monocyte
Immature
macrophage
Macrophages engulf and destroy foreign organisms
Lymphocytes
B
cells
produce
antibodies
T
cells
trigger other cellular immune responses
Eosinophils
Release toxic proteins and free radicals to combat microorganisms and parasitic infections
Lead to tissue inflammation and destruction
Basophils
Responsible for inflammatory reactions during immune response and in the formation of
acute
and
chronic
allergic
diseases
Mast Cells
Regulate
vasodilation
,
vascular
homeostasis
,
immune
responses
,
angiogenesis
, and
venom
detoxification
Complete
Blood
Count
(CBC)
Analysis of blood that provides useful information
Includes
RBC
count
,
hemoglobin
,
hematocrit
, and
WBC
count
Hemoglobin
Specific protein in RBCs where oxygen binds
Hematocrit
Percentage of RBCs in whole blood
Mean Corpuscular Volume
Measure of RBC size
Mean Corpuscular Hemoglobin
Amount of
hemoglobin
inside an
RBC