Endocrinology

• endocrine glands

  ductless, secrete hormones into bloodstream
• bradykinin


  blood vessel dilation
• prostaglandin 


  inflammatory mediator
• gastrin


  gastric acid secretion
• secretin 


  regulation of pH in duodenum
• cholecystokinin


  digestion of fat and protein adipose tissue
• adiponectin


  glucose regulation and fatty acid catabolism
• resistin 


  inflammatory/obesity
• functionality of hormones - endocrine signalling 


  hormones act on target cells distant from site of synthesis
• functionality of hormones - paracine 


  signalling molecules act on neighbouring cells
• functionality of hormones - autocrine 


  signalling molecules act on same cells
• 4 types of hormones

  peptide hormones, amino acid derived hormones, steroid hormones, fatty acid derivatives
• Rathke's pouch 


  depression in the floor of the cranium
• posterior pituitary hormones 


  secretes oxytocin and anti-diuretic hormone
• pars intermedia


  boundary between the anterior and posterior lobes of the pituitary
• cushing's syndrome 


  high levels of ACTH hormone leads to high levels of MSH, leading to abnormal darkening