When a contaminated needle or sharp object pierces the skin of the health worker, body fluid or blood splashes in the eyes, nose or mouth, cut, scratch or abrasion has made contact with blood or body fluid, human bite cuts the skin, for needle stick or other sharp injury: carefully remove the shards or foreign object, wash the site thoroughly with soap and water for at least 30 seconds, for mucous membrane exposure: flush with water or saline for at least 10 minutes, for the eyes, irrigate with water or saline for at least 15 minutes