A strength of this explanation is that stress has practical value.
Addison's disease is a rare disorder of the adrenal glands, people with this cant produce cortisol so the body cant mobilse energy to deal with a stressor.
The lack or cortisol in addisons disease can trigger life threatening addisonian crisis (mental confusion)
To treat addisons disease hydrocortisone, to boost cortisol levels.
Limitation - ignore psychological factors in stress, specifically cogntitve apprasial, working out whether a stressor is a threat.
Speisman; asked students to watch a gruesome medical procedure on film with their heart rates being measured, the heart rates changed when interpreting whats happening during the film, if they believed the procedure to be traumatic they would have increased heart rate.