prescription opioids and heroin produce effects that are similar to endorphin and enkephalin: increased analgesia, decreased alertness, and slowed respiration.
Cocaine, for
example, attaches to structures that regulate dopamine, leading to increases in dopamine activity and producing euphoria
nicotine stimulates cells directly by activating their receptors for acetylcholine
Some drugs mimic neurotransmitters.
Marijuana mimics cannabinoid neurotransmitters
Cocaine, attaches to the dopamine transporter to draws free-floatingdopamine