Sickle Cell Anaemia

• Sickle cell anaemia is a disease in which the red blood cell has a sickle shape instead of a round biconcave shape, controlled by a recessive allele, which causes weakness, aching joints and poor circulation.
• The fact that Sickle Cell Anaemia is recessive means that a heterozygous person can be a carrier: they have the allele but it is not expressed.
• Being a carrier of sickle cell anaemia makes you resistant to malaria
• In equatorial Africa, having sickle cell anaemia causes death. Malaria also causes death. But the carriers have immunity to malaria and have some symptoms of anaemia, in severe cases, they are very weak