Stages of Mitosis

• Interphase


  -Longest phase of the cell cycle

  - Cell grows and carries on a metabolic process

  
• Prophase


  - Chromatin coils into chromosomes; identical strands called chromatids are held together by a centromere​

  - Centrioles direct the assembly of a mitotic spindle​

  - Nuclear envelope and nucleoli have broken down

  
• Metaphase


  - Chromosomes are aligned in the center of the cell on the metaphase plate (center of the spindle midway between the centrioles)​

  - Straight line of chromosomes is now seen

  
• Anaphase


  - Centromere splits​

  - Chromatids move slowly apart and toward the opposite ends of the cell​

  - Anaphase is over when the chromosomes stop moving

  
• Telophase


  - Reverse of prophase​

  - Chromosomes uncoil to become chromatin​

  - Spindles break down and disappear​

  - Nuclear envelope re-forms around chromatin​

  - Nucleoli appear in each of the daughter nuclei

  
• Cytokinesis


  -Division of the cytoplasm​

  - Begins during late anaphase and completes during telophase​

  - A cleavage furrow (contractile ring of microfilaments) forms to pinch the cells into two parts​

  - Two daughter cells exist

  
• G1 phase of Interphase


  Cell grows in size
• S phase of Interphase

  Nucleus and DNA duplicates
• G2 phase of Interphase


  Additional growth and energy is restored