Global scepticism doubts all knowledge, doubting the existence of anything. For example, the brain ๐ง in a vat argument: what if we are not ๐ซ walking, talking, human beings but just a brain in a vat controlled by a supercomputer ๐ฅ๏ธ, directing everything, even our experiences. We cannot prove whether we really exist or if we are in fact just a brain in vat. ๐