For example someone with antisocial personality disorder (APD, or psychopathy) is impulsive, aggressive and irresponsible. A symptom of APD is an "absence of prosocial internal standards associated with a failure to confirm to lawful or culturally normative ethical behaviour". So, someone with APD is socially judged as being abnormal because they don't conform to our moral standards. Psychopathic behaviour would be considered abnormal in a very wide range of cultures