Caused by an infectious agent which is acquired from an infected individual and transmitted to a susceptible host either by direct and indirect contact or through direct inoculation into a broken skin or mucous membrane
Personsimportant for a communicable disease to occur
Infected individual
Susceptible host
Infectious disease
Noteasily transmitted from person to person, requires inoculation
Inoculation
Entrance of microorganism through mechanical means, e.g. biting, puncturing, laceration, open wound
Contagious disease
Easily transmitted from one person to another through droplet, direct, or indirectcontact
B. Epidemiology
The science of the patterns of disease, its occurrence, distribution, or spread and the prevention and control among group of individuals as public health; backbone of disease prevention
Patterns of Disease Occurrence
Sporadic
Endemic
Epidemic
Pandemic
Sporadic
On-and-off attack of the disease; intermittent or occasional; 20% susceptible host, 80% immune
Endemic
Constantly present in a certain locality; 50% immune, 50% susceptible
Epidemic
Number of cases exceeds beyond the normal number of cases for a shortperiod of time; 80% susceptible host, 20% immune
Pandemic
Worldwide epidemic
C. Triad of Disease Causation or the Epidemiologic Triad
Factors that interact to cause a disease
Factors in the Triad of Disease Causation
Agent
Host
Environment
1. Agent
Bacteria, viruses, protozoa, and parasites (biological agents)
Ability of an agent to enter the human body and to move into tissues
Virulence
Strength, potency, or power of the agent to cause a disease
The shorter the incubation period
The more virulent the agent is
Antigenicity
Ability to stimulate antibodyresponse (specific response)
2. Environment
The medium for survival and multiplication of causative agent
Pathogenicity
Ability to cause infection or disease
3. Host
The area where the agent gets its nourishment.
Types of HOST:
a. Humans
b. Animal
c. Plants d. Soil,water,air,milk
e. Fomites
NOTE!: Nonspecific response
Calor
Rubor
Dolor
Tumor Functiolaesa
Types of humans
Carrier - asymptomatic; a person who harbors microorganisms but does not manifest signs and symptoms; most dangerous
Sub-clinically ill - manifests mild signs and symptoms; less dangerous
Clinically ill - manifests ALL the signs and symptoms; least dangerous
Animal
Serves as an intermediate host; secondary or transitional; important in the completion of the life cycle or the microorganisms, e.g. oncomelania quadrasi (snail) in schistosomiasis
Plants
Breeding places of animals
Soil, water, air, milk
Fomites - inanimate objects
All these factors are necessary to cause a disease; an absence of one factor will not cause a disease
If one factor is absent, it will lead to health or wellness
D. Chain of infection
1. Agent
-Causative agent that releases toxicproducts that can be found inside or outside the cell
Types of toxin
Exotoxin - toxic product that can be found outside the cell when the microorganism is still alive
Endotoxin - toxic product inside the cell that is released when the cell is already dead; more dangerous
2. Reservoir
Source of infection; normalarea in the body where the organisms can be found
3. Portals of Exit
Respiratorysystem - sneezing and coughing of respiratory secretions (SMILING is not included)
GIT/Alimentarytract - vomitus and feces
GUT - urine, semen, vaginal discharges
Skin - open wound
Mechanical - bite of an insect or animal
Blood - broken skin or mucosa
Transplacental - mother to fetus
Exudates or discharges - conjunctival secretions, saliva, pus
4. Modes of Transmission
Direct Contact - person to person; needs intimate contact; sexualintercourse, droplet (coughing and sneezing), airborne
Indirect - needs vehicle-borne or vector-borne
Droplet
Less than three feet; less than 30 minutes
Airborne
More than threefeet; morethan30 minutes
Vehicle
Matters through which organism can be transmitted e.g. milk, soil, water