the walls of capillaries are so thin that water, dissolved solutes and gases easily leak out/pass through them - from the plasma, into the tissue fluid that surrounds the cells.
cells exchange material go across their cell membranes with the tissue fluid surrounding them by diffusion, osmosis or active transport
more fluid leaks out of the capillaries
less fluid is returned to the capillaries - excess fluid passes into the lymphatic system and becomes lymph fluid
the lymphatic system is formed from a series of tubes which flow from tissues back to the heart
the lymphatic system connects with the blood system near the heart, where lymph fluid is returned to the blood plasma
lymph nodes: small clusters of lymphatic tissues found throughout the lymphatic system, especially in the neck and armpits
there are large numbers of lymphocytes in lymph nodes
tissues associated with the lymphatic system (like bone marrow) produces the lymphocytes