4.4 Changes in Signal Transduction Pathways

• Changes in Signal Transduction Pathways alter cellular responses.
• Mutations in any part of the receptor protein or in any part of the signaling pathway may affect the downstream components by altering the subsequent transduction of the signal.
• One disruption in a pathway can affect the downstream reactions.
• Chemicals that interfere with any component of the signaling pathway may activate or inhibit the pathway.