Candidate genes: MAOA gene: Brunner et al (1993) analysed the DNA of a Dutch family with 8 male members who had histories of impulsive and violent crimes and found they shared a gene for low MAOA.
Diathesis stress: Epigenetics proposes that genes are switched on by epigenomes, which are in turn affected by environmental factors, e.g. maltreatment in childhood.
Impulsive and behavioural difficulties are potential symptoms of XXY Syndrome, which could lead to crime as individuals may be picked on for appearance, more impulsive, and may be less likely to think through the consequences.
Abnormalities in the amygdala have been associated with psychopathy, which is characterised by features such as narcissism, fearlessness, emotional detachment, grandiose sense of self worth, lack of remorse or guilt.
Raine et al (1990) investigated fear responses in 1,795 3 year olds, and found that those who went on to commit crime were less likely to exhibit fear when the first tone was played, due to abnormal amygdala functioning.
Charles Whitman, a spree killer, had a brain tumour pressing on his amygdala, which can lead to crime because people may be more reactive (fight or flight).
Correlation is not cause, as other areas of the brain may be implicated, for example the orbitofrontal cortex in the frontal lobe is thought to regulate self control and reduced functioning is associated with violent outbursts.