digestive system consists of mouth, esophagus, stomach, intestines, and the accessory organs
mouth and salivary glands prepare food for swallowing, detect taste, start digestion with anylase and lingual lipas
esophagus moves food to stomach by peristaltic wavs initiated by swallowing
stomach secretes gastric juices containing acid, enzymes, and hormones which mixes with food and turns it into chyme then kills microoganisms with acid
liver- produces bile to aid fat digestion and absorption
gallbladder- stores and concentrates bile and releases it to the small intestine
pancreas- secretes pancreatic juices containing digestive enzymes and bicarbonate into the small intestine
small intestine- mixes chyme with bile and pancreatic juice and does most of the absorption then transports remaining residue to large intestie
large intestine (colon)- absorbes water and electrolytes and forms and stores feces
rectum- holds and expels feces via the anus
gi wall has 4 layers 1. mucosa 2. submucosa 3. muscle 4. serosa
lower esophogeal sphincter- prevents reflux of stomach into esophagus
pyloric sphincter- control flow of stomach contents into small intestine
swallowing- epiglottis cloes over the larynx to prevent food from entering the trachea
stomach- food enters stomach via the lower esophageal sphincter. little digestion happens here the stomach is mainly just a holding tank. it secretes gastric juices that contain hydrochloric acid, pepsinogen (digests protein), and gastrin which helps control the release of hci and pepsinogen. also secretes mucus that lubricate and protect stomach and lining from hci. nsaids inhibit prostaglandins productions of mucus
2. small intestine is divided into three sections duodenum, jejunum, ileum. inside has circular folds and villi that help move food along. villi are lined with enterocytes that secrete enzymes and absorb nutrients
digestion in the small intestine depends on secretions from the accessory organs
secretions from the ao's are delivered through the common bile duct and pancreatic duct
liver produces bile that contains cholesterol and emulsifies fat
5 main hormones in regulation of digestive processes are gastrin, secretin, cholecystokinin (cck), somatostatin, and glucose dependent insulinotropic peptide (gip)
ghrelin- increases appetite and food intake
gastrin- triggers the stomach to release hci and pepsinogen and stimulates gastric and intestinal motility
somatostatin- inhibits release of gi hormones, slows gastic emptying, gi mobility, and blood flow
passive diffusion- nutrients move from an area of low concentration
facilitated diffusion- high to low w help
active transport- low to high w help
3. large intestine- small intestine empties into large through the ileocecal valve. has 3 main parts colon, rectum, and anus. 3 main functions are to house microbiota, absorb water and electrolytes, and to form and expel feces
probiotics- LIVE microorganism that colonize the large intestine and prevent diarrhea, food allergies, ibs, ibd
prebiotics- non-digestible food ingredients that promote the grown of beneficial bacteria
gerd- 2 or more times a week of heartburn and acid reflux
ulcers are caused by helicobacter pylori and heavy use of nsaids