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Cards (13)

    • In the longitudinal view there will be parallel fibers and multiple peripheral nuclei.
    • In the cross-sectional view there will be peripheral nuclei and the appearance of "cylindrical bundles".
    • A specialized terminology is used to describe muscles or muscle tissue. "sarkos" which means "flesh".
    • The cell membrane is called the sarcolemma, the cytoplasm is called the sarcoplasm, the endoplasmic reticulum is called the sarcoplasmic reticulum, and the muscle cell itself is called a muscle fiber.
    • This terminology is specific to muscles and is derived from the Greek root "sarkos" which means "flesh".
    • Skeletal muscles can be described as "bundles within bundles within bundles".
    • Each individual skeletal muscle fiber consists of bundles of myofibrils and is encased in a connective tissue called the endomysium.
    • Groups of skeletal muscle fibers are in tum gathered into bundles which are wrapped in more connective tissue called the perimysium.
    • These bundles are in turn grouped together and enclosed in a layer of dense connective tissue called the epimysium which forms individual muscles.
    • Each individual muscle is wrapped in a tough layer of fibrous connective tissue called the fascia.
    • These are continuous with tendons and the periosteum of bones.
  • Muscle Fibers (myocytes or muscle cells)
    • are the basic unit of the muscle itself.
    • smallest functional unit or cell that a muscle can be divided into.
    • are made up of smaller sub-units called myofibrils.
    • These are in turn composed of threadlike myofilaments which are composed of the proteins actin and myosin.
    • Actin filaments are thin and appear as light bands under the microscope, while myosin filaments are thick and appear dark.
    • These have an overlappingstructure and are held together by chemical cross bridges.
    • The overlapping structure gives skeletal muscle a banded or striped look under the microscope.
  • These alternating light and dark bands are called striations and give skeletal muscle its alternate name, and more accurate name, voluntary, striated muscle.
    • A closer look at the striations reveals that the myofibrils are composed of repeating units of actin and myosin called sarcomeres.
    • sarcomere represents the smallest individual contractile unit of al muscle fiber.
    • It is measured from the point where actin myofilaments overlap to the next actin overlap.
    • The actin overlap is called the "Z" line, so a complete sarcomere extends from Z line to Z line.
  • Sarcomere
    •  is flanked by 2 protein structures known as Z discs.
    • The portion of the sarcomere which contains the thick filament is known as the A band.
    • A stands for anisotropic which is a fancy way of saying that it appears dark under the microscope.
    • The A band contains a zone of overlap (btwn thick & thin filaments) and an H zone which contains only thick filaments
  • Skeletal muscle fibers
    not all alike in composition and function. For example, muscle fibers vary in their content of myoglobin.
    Myoglobin - the red-colored protein that binds oxygen in musclefibers.
  • Skeletal muscle fibers that have a high myoglobin content are termed red muscle fibers and appear darker (the dark meat in chicken legs and thighs); those that have a low content of myoglobin are called white muscle fibers and appear lighter (the white meat in chicken breasts).
  • Myofilament
    Thin myofilaments
    • Composed of actin protein
    • Associated with troponin and tropomyosin proteins
    Thick myofilaments
    • Composed of myosin protein
    • Form the cross-bridges