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mod 5
5.3.1 transition metals
cisplatin
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Savannah Mhonda
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Cards (2)
Platin
binds to
DNA
of
cancer
cells and stops
cancer
cells
dividing.
It can also prevent the
replication
of
healthy
cells by
bonding
on to
healthy
DNA which may lead to unwanted
side
effects like
hair
loss.
The Pt(II) complex cisplatin is used as an anticancer drug.
only works as two chloride ions are displaced and the molecule joins on to the DNA. In doing this it stops the replication of cancerous cells.
explain how it bonds to DNA molecule- generally a combination of dative covalent bonding and hydrogen
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