[Nestadt et al]- research to support genetic vulnerability form twin studies- 68% Identical twins and 31% Non identical shared OCD- family member with ocd equals 4x more likely
[Cromer et al]- Biologicalreductionism as he found OCD was caused because of traumaticevents in some cases
Evaluate Neural explanation for OCD
Cannot establish casual relationship between abnormal brain functioning and OCD
Research to support low levels of serotonin affect OCD [zohar et al]- antidepressants that work purely on serotonin levels reduced OCD symptoms
Outline Bio approach to treating OCD
Treatments involving drugs- which affect neurtransmitter levels
SSRI's - antidepressants that work on the serotonin system in the brain
Serotonin released by the presynaptic neuron , travels across a synapse. chemically conveys the signal to the postsynaptic neuron where it's reabsorbed, broken down and reused
SSRI's prevent reabsorption and breakdown- which means serotonin can continue to stimulate
3-4 months of daily use for SSRI''s to have impacts on symptoms
Alternatives to SSRI's
Tricyclics- same effect but more sever side effects- kept in reserve for individuals who don't respond to SSRIs
SNRI's- increases levels of serotonin and noradrenaline
A limitation of treatments into OCD
SSRI's have serious side effects- indigestion, blurred vision and loss of sex drive- more common if taking tricyclic drugs= reduces quality of life - may stop taking them- so less effective
2 strength of research into treatment of OCD
+ Evidence for it's effectiveness [ soomro et al]- 17 studies vs placebo - symptoms reduce for 70% people taking SSRI's and the rest of the 30% can take a combination of other drugs+ therapy- this reduces symptoms severity and increases quality of life
+ Costeffective+ Non-disruptive- can manufacture thousands of tablets/liquids in time it takes to conduct one session of psychological therapy = good value for NHS - can be taken whenever- does not take much time= popular treatment