In the pathophysiology of Blackleg, spores of Clostridium chauvoei are eaten in contaminated feed or soil, enter the bloodstream and lodge in organs and tissues, including the muscle.
Blackleg in cattle begins with the animal becoming lame with swelling of a muscle, stopping grazing, and producing gas under the skin that produces a crackling sensation when rubbed with the hand (Crepitus).
Diagnosis of Blackleg in cattle can be done through ultrasonographic examination of affected areas like the heart, anaerobic culture of affected tissues, biochemical identification of organisms in tissue samples, and postmortem examination.
Treatment/prevention of Blackleg in cattle includes usage of multivalent vaccine (5in1 or 7in1), and some cases may be treated early with antibiotics but would still suffer permanent deformity due to the destruction of muscles.