A fecal sample is a solid body waste discharged from the large intestine through the anus by the process of defecation, made of cellulose, other indigestible food matter, water, and bacteria
About 100 to 300 grams of fecal material is excreted by an average adult daily, the residue of approximately 10 liters of liquid material that enters the GI tract each day
Laboratory analysis of feces includes macroscopic examination (volume, odor, shape, color, consistency, presence of mucus), microscopic examination (leukocytes, epithelial cells, meat fibers), and chemical tests for specific substances (occult blood, trypsin, estimation of carbohydrates)
Proper specimen collection and handling, accurate sample identification, ensuring all supplies are appropriate for collection, and timely transport of specimens to the laboratory are essential
Fecal analysis aids in diagnosing disorders related to gastrointestinal (GI) bleeding or medication therapy that results in bleeding, determining intestinal parasitic infestation, diagnosing suspected inflammatory bowel syndrome (IBS), identifying the cause of diarrhea, investigating disorders of protein digestion, screening for colorectal cancer, and screening for cystic fibrosis
Medications that irritate the gastric mucosa such as non-steroidal anti-inflammatory medicines (NSAIDs), anticoagulants, colchicine, corticosteroids, phenylbutazone, and iron preparations can cause positive results for occult blood
High doses of vitamin C (more than 250 mg per day) can cause false negative occult blood, while dietary intake high in red meat, certain vegetables (radish, turnips, cauliflower, broccoli), and fruits (bananas, apples, cantaloupe) can cause false-positive results for occult blood
Colonoscopy is a common diagnostic test that utilizes a flexible fiberoptic colonoscope inserted into the rectum to visually examine the large intestine (colon) lining
Indications for colonoscopy include screening for colon and rectal cancer, detecting and evaluating inflammatory and ulcerative bowel disease, locating the source of lower GI bleeding, determining the cause of lower GI disorders, assisting in diagnosing colonic strictures and benign or malignant lesions, evaluating the colon postoperatively for recurrence of polyps and malignant lesions, investigating iron-deficiency anemia of unknown origin, and removing colon polyps
Contraindications for colonoscopy include patients with bleeding disorders, patients who had a recent acute myocardial infarction or abdominal surgery, insufficient bowel preparation, retained barium in the intestine from a previous diagnostic procedure, inability of the patient to tolerate the introduction or retention of barium, air, or both in the bowel, and sigmoid colon fixation due to inflammatory bowel disease, surgery, or radiation therapy
When the scope is advanced through the sigmoid, the patient's position is changed to supine to allow passage into the transverse colon. Air is insufflated through the tube during the passage to help in visualization
Instruct the patient to take deep breaths to aid in the movement of the scope down through the ascending colon to the cecum and into the terminal portion of the ileum
Monitor vital signs and neurological status every 15 minutes for 1 hour, then every 2 hours for 4 hours, or as ordered. Assess temperature every 4 hours for 24 hours