URTI (bacterial and viral)
Streptococcus pneumoniae, haemophilus influenzae, Moraxella catarrhalis
Higher incidence in children
Due to URTI susceptibility (has underdeveloped immune system)
Medical conditions such as Down Syndrome (shorter eustachian tube and narrow esopharyngeal airway)
Tendency to self inoculate (cross contamination)
Breastfeeding can lower the risk of acute otitis media because breast milk has antibody protection
Smoking (2nd hand smoking)