IS

• Product of B cells

  Antibodies
• Product of T cells and/or NK cells

  Cytotoxins ( Perforins, Granzymes )
• T cells have defense against:

  Tumors, Graft rejection, Fungal, Viral
• B cells have defenst against

  Bacterial infections
• NK cells have defense against

  Tumor cells, Virus-infected cells
• Primary/Central Lymphoid Organs

  Thymus, Bone Marrow
• Seconday/Peripheral Lymphoid organs

  Spleen, Lymph nodes
• [SPLEEN] contains macrophages that destroys old RBCs

  Red pulp
• Bone Marrow is the site for?

  B cell development, Hematopoiesis
• [THYMUS] mature T cells

  Medulla
• [THYMUS] immature T cells

  Cortex
• [LYMPH NODES] Germinal center cells

  Plasma cells, Memory cells
• [LYMPH NODES] less densely populated

  Medulla
• [SPLEEN] White pulp has _ and _

  Lymphocytes, Macrophages
• [LYMPH NODES] produces T cells

  Paracortex
• [LYMPH NODES] Outer Cortex produces

  B cells, Dendritic Cells, Marcophages
• [SPLEEN] _ produces B cells

  Primary Follicles
• [SPLEEN] Marginal zones produces _

  Dendritic cells