A collection of all the chemical compounds that have been added to the entirety of one's DNA (genome) as a way to regulate the activity (expression) of all the genes within the genome
Treat DNA with bisulfite to convert unmethylated cytosines to uracil, then sequence the DNA to distinguish between methylated and unmethylated cytosines
Addition of methyl groups by histone methyltransferases (HMTs); can either activate or repress gene expression depending on the specific residue methylated