Scientific discipline that investigates the body's structure and its relationship
Cytology
Microscopic examination of cells obtained from the body (as by aspiration or scraping) for diagnostic purposes
Histology
Study of microanatomy of cells, tissues, and organs as seen through a microscope. It examines correlation between structures and functions
Histotechniques
Techniques for processing the tissues, whether biopsies, larger specimens removed by surgery or tissues from autopsy
Histotechnologist
A person who does the tissue processing and makes the glass microscopic slides
Pathology
Study of structural, biochemical and functional changes in cells, tissues and organs that underlie disease
Physiology
Scientific investigation of the normal process or functions of living things
Basophilic
Base-loving; a structure that stains with basic dye like hematoxylin
Acidophilic
Acid-loving; a structure that stains with acidic dye like eosin
Perimysium
Connective tissue sheath that surrounds a group of muscle fibers to form a bundle known as fascicle
Perineurium
Connective tissue sheath that surrounds a group of nerve fibers to form a bundle known as fascicle
Perichondrium
Connective tissue sheath that may cover certain types of cartilage
Endomysium
Connective tissue sheath that surrounds an individual muscle fiber
Endoneurium
Connective tissue sheath that surrounds an individual nerve fiber
Endosteum
Layer of connective tissue that covers bone facing the marrow cavity, and trabeculae of bone within the marrow cavity
Epithelium
Tissue composed of cells that cover body surfaces and line hollow structures or cavities referred to as the innermost layer
Epidermis
Uppermost layer of the skin that lies upon the dermis
Epimysium
Dense connective tissue sheath surrounding a collection of fascicles that comprise the entire muscle
Epineurium
Dense connective tissue sheath surrounding a collection of fascicles that comprise an entire nerve
Extracellular matrix (ECM)
Matrix of components secreted by cells that reside in the intervening spaces between cells
Intramembranous ossification
Form of osteogenesis where bone is formed within mesenchyme
Interstitial
Growth within a matrix. Chondrocytes within a cartilage matrix divides producing new cells and matrix to allow for growth
Interstitial lamellae
Remnants of concentric lamellae formed during bone remodeling and found between osteons
Fibroblast
Principal cell of connective tissue responsible for the synthesis of collagen, reticular and elastic fibers as well as other components of ground substance
Leukocyte
White blood cell
Stratified
An epithelium composed of many layers of cells
Pseudostratified
An epithelium that appears to be composed of many layers but is in fact, not
Lamina
Term used to describe structures that exhibit a plate-like appearance or layers
Lamella
Diminutive of lamina and is also used to refer to a layer. In mature bone, the arrangement of collagen fibers and other bone components are described as lamella
Tunica
Refers to a layer of tissue ensheathing a structure
Zona
Histologically, the term zona refers to the zone or belt. Usually used for adrenal glands, wherein the cortex being subdivided into 3 zones: zona glomerulosa, zona fasciculata, and zona reticularis
Osteoblast
Osteoprogenitor cells that differentiate into osteoblasts. These cells retain the ability to divide and are able to secrete osteoid
Osteocyte
Principal cell types of bone involved in maintenance of the bone matrix
Osteoclast
Cells derived from the mononuclear phagocytic system that are responsible for remodeling bone
Osteogenesis
Process by which bone forms
Chondroblast
Cells responsible for laying down cartilage during chondrogenesis
Chondrocyte
Principal type of bone involved in maintenance of the cartilage matrix
Chondroclast
Cells derived from the mononuclear phagocytic system that are responsible for remodeling cartilage
Chondrogenesis
Process by which cartilage forms
Spicule
A small sharp process often encountered in descriptions of spongy bone and in the process of osteogenesis where osteoid is laid down in spicules, which then coalesce to form larger structures known as trabeculae