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ANAPHY LEC
MUSCULAR
Contraction cycle
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Cards (6)
Neuron signals (nerve impulses)
1. Released from the
spinal cord
2. Release of
calcium
3. Synaptic pump releases
acetylcholine
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Muscle contraction
1.
Acetylcholine
attaches to
acetylcholine
receptors in muscle fibers
2. Muscle is in an
excitation
state
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Cross-bridge
cycle
Connection between the head of
myosin
filaments and
actin
filaments causes action
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ATP hydrolysis
1. ATP hydrolyses to
ADP
and
phosphate
2.
Myosin
is ready to attach to
actin filaments
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Calcium attachment
1.
Calcium attaches to troponins
2.
Exposes the site of attachment in actin filaments
3.
Power stroke state where the sarcomere shortens
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Muscle contraction and relaxation
1.
ATP
plays an important role in the separation of the myosin and
actin
2. When the muscle is in a resting position,
tropomyosin
and troponin block the myosin-binding sites on
actin
filaments
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