Implantation and successful replication of an organism in the tissue of the host resulting in signs and symptoms as well as immunologic response
Carrier
An individual who harbors the organism and is capable of transmitting it to a susceptible host without showing manifestations of the disease
Communicable Disease
An illness caused by an infectious agent or its toxic products that are transmitted directly or indirectly to a well person through an agency, and a vector or an inanimate object
Contact
Any person or animal who is in close association with an infected person, animal or freshly soiled materials
Contagious Disease
A disease that is easily transmitted from one person to another through direct or indirect means
Communicable diseases are caused by pathogens that spread through direct contact with infected individuals or indirectly via contaminated objects or substances.
Disinfection
The destruction of pathogenic microorganism on inanimate objects by directly applying physical or chemical means
Concurrent disinfection
1. Method of disinfection done immediately after the infected individual discharges infectious material/secretions
2. When the patient is still the source of infection
Terminal disinfection
Method of disinfection applied when the patient is no longer the source of infection
Habitat
A place where an organism lives or where an organism is usually found
Host
A person, animal or plant on which a parasite depends for its survival
Infectious Disease
Transmitted not only by ordinary contact but requires direct inoculation of the organism through a break on the skin or mucous membrane
Isolation
The separation from other persons of an individual suffering from a communicable disease
Quarantine
The limitation of freedom of movement of persons or animals which have been exposed to communicable disease/s for a period of time equivalent to the longest incubation period of that disease
Reservoir
Composed of one of more species of animal or plant in which an infectious agent lives and multiplies for survival and reproduces itself in such a manner that it can be transmitted to man
Epidemiology
The study of occurrences and disturbance of diseases as well as the distribution and determinants of health states of events in specified population and application of this study to the control of health problems
Uses of epidemiology
Study the history of the health population and the rise and fall of disease and changes in their character
Diagnose the health of the community
Study the work of health services with a view of improving them
Estimate the risk of disease, accident, defects and the chances of avoiding them
Complete the clinical picture of chronic disease and describe their history
Epidemiologic Triangle
Consists of three components - host, environment and agent
Host
Any organism that harbors and provides nourishment for another organism
Agent
Intrinsic property of microorganism to survive and multiply in the environment to produce disease
Environment
The sum total of all external conditions and influences that affect the development of an organism which can be: Biological, Social, Physical
Types of disease occurrence and distribution
Sporadic
Endemic
Epidemic (Outbreak)
Pandemic
Sporadic
Intermittent occurrence of a few isolated and unrelated cases in a given locality. Cases are few and scattered
Endemic
Continuous occurrence throughout a period of time, of the usual number of case in a given locality. The disease is therefore always occurring in the locality and the level of occurrence is more or less constant through a period of time
Epidemic (Outbreak)
Unusually large number of cases in a relatively short period of time
Pandemic
The simultaneous occurrence of epidemic of the same disease in several countries
Modes of disease transmission
Airborne
Vehicle
Vector
Contact
Contact Transmission
Most common mode of transmission. Includes direct contact (person to person transfer), indirect contact (susceptible person comes in contact with a contaminated object), and droplet spread ( transmission through contact with respiratory secretions when the infected person coughs, sneezes or talks)
Droplet Spread
Transmission through contact with respiratory secretions when the infected person coughs, sneezes or talks
Airborne Transmission
Occurs when fine microbial particles or dust particles containing microbes remain suspended in the air for a prolonged period
Vehicle Transmission
Non-living carrier. Transmission of infectious disease through articles or substance that harbor the organism until it is ingested or inoculated into the host
Vector-borne Transmission
Occurs when intermediate carriers, such as fleas, flies and mosquitoes transfer the microbes to another living organism
Portal of Entry
The venue the organism gains entrance into the susceptible host. The infective microbes use the same avenues when they exit from the reservoir
Susceptible Host
When the defenses are good, no infection will take place. However, in weakened host, microbes will launch an infectious disease
Indirect Contact Transmission occurs when a person touches something contaminated with pathogens (such as doorknobs, utensils, bedding) and then touches their own mouth, nose, eyes, or broken skin.
Inactivated (killed organism)
Not long lasting
Multiple doses needed
Booster dose needed
Attenuated (live, weakened organism)
Single dose needed
Long lasting immunity
Isolation
Separation of patients with communicable disease from other so as to prevent or reduce transmission or infectious agent directly or indirectly
Categories Recommended in Isolation
Strict Isolation
Contact Isolation
Respiratory Isolation
TB Isolation
Enteric Isolation
Reverse/Neutropenic Isolation
Standard Precaution
Universal Precaution + Body Substance Isolation (BSI)
Universal Precaution
Intended to prevent parenteral mucous membrane and non-intact skin exposure of healthcare workers to blood borne pathogens