1. Pre-eruptive/Prodromal stage (Forchheimer's spots, with or without slight fever, headache, mild sore throat, loss of appetite, runny nose, leukopenia)
2. Eruptive stage (rash - oval, rose-red papules, begins on face and covers entire body in 24 hours, enlargement of lymph nodes)
Most highly contagious childhood disease, affects adults more severely, one attack confers lifelong immunity, virus may become dormant and lead to Herpes Zoster
1. Pre-eruptive/Prodromal stage (with or without low-grade fever, malaise, muscle pains)
2. Eruptive stage (exanthem appears one at a time and disappears in same manner, starts as macules, papules, successive crops of vesicles, occasionally pustules, spread throughout body in 6 hours, ends as granular crusts/scabs)
1. Pre-eruptive / Prodromal Stage: Fever for 3-4 days, headache, sore throat/colds, body malaise, Excessive mucopurulent lacrimal discharge, Stimson sign, Koplik's spots, Forcheimer's spots, With or without slight fever, headache, mild sore throat, loss of appetite, runny nose, Leukopenia during febrile stage
2. Eruptive Stage: Maculopapular rashes, Reddish in color and blotchy in appearance, First appearing around the 3rd day, Cephalocaudal appearance, Photosensitivity, Rash - cardinal sign: Oval, rose-red papules about the size of a pinhead, Begins on the face, covers the entire body in 24 hours (cephalocaudal), Enlargement of the lymph nodes - suboccipital, postauricular and postcervical
3. Post Eruptive Stage: Cephalocaudal disappearance of the rashes, Fine, branny desquamation of the skin, Rashes disappear on the 3rd day, Lymph nodes subside
Prevention: Passive immunization - gamma globulin if the child has been exposed; immunity lasts for 2-3 weeks, Active immunization - Measles-Mumps-Rubella (MMR) or measles vaccine at 9 months of age or as early as 6 months, 0.5 ml subcutaneous; may experience fever for 2-3 days and rashes